prof. dr. R.M. (Raymond) Schiffelers
prof. dr. R.M. (Raymond) Schiffelers
- Central Diagnostic Laboratory
Research Programs
Biography
Biography
Raymond Schiffelers studied Bio-Pharmaceutical Sciences at Leiden University (1990-1995). After an industrial traineeship at SmithKline Beecham Pharmaceuticals (UK) he did his PhD in medical microbiology at Erasmus University Rotterdam on liposomal targeting of antimicrobial agents (1996-2001). Subsequently he became post-doc at Utrecht University working on liposomes targeting tumor vasculature. In 2002-2003, at Intradigm Co (USA) he expanded his tumor vasculature-targeting work with polymers for delivery of siRNA. After his return to Utrecht University he became assistant and then associate professor. He co-invented OncoCort® a nanomedicine formulation of corticosteroids that will enter clinical trials in 2015. In 2011, he moved to the Laboratory for Clinical Chemistry & Hematology of the University Medical Center Utrecht to work on nanomedicines, both for diagnosis and therapy. In particularly, he focuses on extracellular vesicles in the circulation as inspiration for new drug delivery systems and diagnostic readouts. He is founding member of the International Society for Extracellular Vesicles (ISEV) founding member and member organizing committee for the ISEV2014-annual meeting, Associate Editor of the Journal Extracellular Vesicles and editor of the International Journal of Pharmaceutics and the Journal of Controlled Release. He is Founder of EXCYTEX-an extracellular vesicle-based company and member of the Scientific Advisory Board for a number of start-up companies.
Side Activities
Without remuneration
President European Technology Platform Nanomedicine
Associate Editor Journal of Extracellular Vesicles & Drug Delivery and Translational Research
Founder/Share holder (<5%)/Scientific Advisor Excytex bv
Member Scientific Advisory Board Anjarium BioSciences
Member Scientific Advisory Board SentryX bv
Remuneration for department
Editor International Journal Pharmaceutics
Editor Journal Controlled Release
Part-time employment
Nanocell Therapeutics BV
Fellowship and Awards
Vidi 2007 ‘Targeting inflammation to fight cancer’
Galenus Research Award 2009
ERC Consolidator grant 2010 260627 ‘Microvesicle-inspired drug delivery systems’
ERC Proof of Concept grant 2012 29744 ‘TargetMV’
Research Output (183)
Estapé Senti Mariona, García Del Valle Lucía, Schiffelers Raymond M 1 Feb 2024, In: Advanced Drug Delivery Reviews. 206 , p. 1-17 17 p.
Fang Juntao, Yang Qiangbing, Maas Renée G C, Buono Michele, Meijlink Bram, Lotgerink Bruinenberg Dyonne, Benavente Ernest Diez, Mokry Michal, van Mil Alain, Qian Li, Goumans Marie-José, Schiffelers Raymond, Lei Zhiyong, Sluijter Joost P G 17 Jan 2024, In: Stem Cell Research & Therapy [E]. 15 , p. 19
Ilahibaks Nazma F, Kluiver Thomas A, de Jong Olivier G, de Jager Saskia C A, Schiffelers Raymond M, Vader Pieter, Peng Weng Chuan, Lei Zhiyong, Sluijter Joost P G Jan 2024, In: Journal of Extracellular Vesicles. 13
van Solinge Thomas S, Friis Kristina Pagh, O'Brien Killian, Verschoor Romy L, van Aarle Jeroen, Koekman Arnold, Breakefield Xandra O, Vader Pieter, Schiffelers Raymond, Broekman Marike 15 Dec 2023, In: International Journal of Pharmaceutics: X. 6 , p. 1-8
Zeng Ye, Estapé Senti Mariona, Labonia M. Clara I., Papadopoulou Panagiota, Brans Maike A.D., Dokter Inge, Fens Marcel H., van Mil Alain, Sluijter Joost P.G., Schiffelers Raymond M., Vader Pieter, Kros Alexander 12 Dec 2023, In: ACS Nano. 17 , p. 23466-23477 12 p.
Fang Juntao, de Bruin Alain, Villunger Andreas, Schiffelers Raymond, Lei Zhiyong, Sluijter Joost P G 1 Aug 2023, In: Protein & cell. 14 , p. 560-578 19 p.
van Vliet Emile F, Knol Maarten J, Schiffelers Raymond M, Caiazzo Massimiliano, Fens Marcel H A M 24 Jun 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 360 , p. 212-224 13 p.
van Kammen C M, van Woudenberg S J, Schiffelers R, Terstappen F, Lely A T 20 Jun 2023, In: Journal of controlled release : official journal of the Controlled Release Society. 360 , p. 57-68 12 p.
Swart Laura E, Fens Marcel H A M, van Oort Anita, Waranecki Piotr, Mata Casimiro L Daniel, Tuk David, Hendriksen Martijn, van den Brink Luca, Schweighart Elizabeth, Seinen Cor, Nelson Ryan, Krippner-Heidenreich Anja, O'Toole Tom, Schiffelers Raymond M, Kooijmans Sander, Heidenreich Olaf Jun 2023, In: Pharmaceutics. 15 , p. 1-16
Ilahibaks Nazma F., Ardisasmita Arif I., Xie Songpu, Gunnarsson Anders, Brealey Joseph, Vader Pieter, de Jong Olivier G., de Jager Saskia, Dekker Niek, Peacock Ben, Schiffelers Raymond M., Sluijter Joost P.G., Lei Zhiyong Mar 2023, In: Journal of Controlled Release. 355 , p. 579-592 14 p.