dr. M.A.E. (Minke) Rab MSc
dr. M.A.E. (Minke) Rab MSc
- Central Diagnostic Laboratory
Research Programs
Biography
Biography
Dr. Minke Rab is a Clinical Scientist, who graduated from medical school in 2010 after completing the Selective University Medical Masters (SUMMA) program at the UMCU, The Netherlands. In 2015 she started her PhD project on hereditary hemolytic anemias (UMCU, 2015-2019). After her internal medicine residency, she completed a two-year fellowship in Hematology (UMCU) while combining her clinical work with laboratory research. Thereafter, she has been appointed as hematologist at the Erasmus University Medical Center Rotterdam, where she is involved in the expertise center for hemoglobinopathies. Next to her clinical work, she works as assistant professor at the Central Diagnostic Laboratory-Research, UMCU on biomarker development in hereditary hemolytic anemias. A key achievement is the development of oxygenscan-related biomarkers reflecting RBC sickling on which she co-authored nine papers. She led the development of the oxygenscan from an early prototype stage into a technique that is now incorporated in various clinical trials in the US, Europe, and Africa.
Her research focusses on biomarker development in sickle cell disease and its applicability to assess novel therapies both in vitro and in vivo. For these kind of projects funding was obtained from Eurostars, RVO, Agios pharmaceuticals, Axcella Health and RR Mechatronics. It is the ambition of dr. Rab to further elucidate the crucial pathophysiological features of sickle cell disease, in order to find the best treatment, that is globally available, for this understudied disorder. Being a clinician-scientist, she is in an excellent position to bridge the gap between bench and bedside.
Research Output (20)
van Dijk Myrthe J., van Oirschot Brigitte A., Harrison Alexander N., Recktenwald Steffen M., Qiao Min, Stommen Amaury, Cloos Anne Sophie, Vanderroost Juliette, Terrasi Romano, Dey Kuntal, Bos Jennifer, Rab Minke A.E., Bogdanova Anna, Minetti Giampaolo, Muccioli Giulio G., Tyteca Donatienne, Egée Stéphane, Kaestner Lars, Molday Robert S., van Beers Eduard J., van Wijk Richard Dec 2023, In: American Journal of Hematology. 98 , p. 1877-1887 11 p.
Rab Minke A E, Kanne Celeste K, Boisson Camille, Bos Jennifer, van Oirschot Brigitte A, Houwing Maite, Renoux Céline, Bartels Marije, Rijneveld Anita W, Nur Erfan, Cnossen Marjon H, Joly Philippe, Nader Elie, Fort Romain, Connes Philippe, van Wijk Richard, Sheehan Vivien A, van Beers Eduard J 17 Nov 2023, In: Blood Advances. 8 , p. 276-286 11 p.
van Dijk Myrthe J, Rab Minke A E, van Oirschot Brigitte A, Bos Jennifer, Derichs Cleo, Rijneveld Anita W, Cnossen Marjon H, Nur Erfan, Biemond Bart J, Bartels Marije, Jans Judith J M, van Solinge W W, Schutgens Roger E G, van Wijk Richard, van Beers Eduard J 7 Nov 2023, In: Blood Advances. 7 , p. 7539-7550 12 p.
van Dijk Myrthe J, de Wilde Jonathan R A, Bartels Marije, Kuo Kevin H M, Glenthøj Andreas, Rab Minke A E, van Beers Eduard J, van Wijk Richard 12 Jun 2023, In: Blood Reviews. 61
van Dijk Myrthe J, Rab Minke A E, van Oirschot Brigitte A, Bos Jennifer, Derichs Cleo, Rijneveld Anita W, Cnossen Marjon H, Nur Erfan, Biemond Bart J, Bartels Marije, Jans Judith J M, van Solinge Wouter W, Schutgens Roger E G, van Wijk Richard, van Beers Eduard J 5 Apr 2022, In: American Journal of Hematology. 97 , p. E226-E229
Sheehan Vivien A., van Beers Eduard J., Connes Philippe, van Wijk Richard, Rab Minke A.E. 2022, In: British Journal of Haematology. 197 , p. e61-e62
Rab Minke A E 29 Sep 2021, 290 p.
Boisson Camille, Rab Minke A E, Nader Elie, Renoux Céline, Kanne Celeste, Bos Jennifer, van Oirschot Brigitte A, Joly Philippe, Fort Romain, Gauthier Alexandra, Stauffer Emeric, Poutrel Solene, Kebaili Kamila, Cannas Giovanna, Garnier Nathalie, Renard Cécile, Hequet Olivier, Hot Arnaud, Bertrand Yves, van Wijk Richard, Sheehan Vivien A, van Beers Eduard J, Connes Philippe 5 Apr 2021, In: Cells. 10 , p. 1-11
Berrevoets M C, Bos J, Huisjes R, Merkx T H, van Oirschot B A, van Solinge W W, Verweij J W, Lindeboom M Y A, van Beers E J, Bartels M, van Wijk R, Rab M A E 25 Mar 2021, In: Frontiers in Physiology. 12 , p. 1-10
Rab Minke A E, Bos Jennifer, van Oirschot Brigitte, Straaten Stephanie van, Kosinski Penelope A, Chubukov Victor, Kim Hyeryun, Mangus Heidi, Schutgens Roger E G, Pasterkamp Gerard, Dang Lenny, Kung Charles, van Beers Eduard J, van Wijk Richard 10 Mar 2021, In: Blood. 137 , p. 2997-3001 5 p.