prof. dr. ir. J.J.W. Lagendijk

Full Professor

  • Medical Physics Group

prof. dr. ir. J.J.W. Lagendijk

Research Programs


Jan Lagendijk's research focus is the application of MRI in radiotherapy. MRI is used for all aspects of radiotherapy. With MRI it is possible to find and characterize tumours. Jan Lagendijk is developing the MRI linac system to visualize the tumour and its surrounding tissues, in real time, at the moment of treatment. This to guide and optimize treatment and to prevent that normal tissues are being irradiated. Jan Lagendijk also uses MRI for response assessment, to quantify the impact of treatments. His motto is ‘See what you treat’. The technology, he develops, must create the next generation radiotherapy standard. Together with Elekta and Philips he is introducing this MRI technology in routine clinic.

Side Activities

  • Member Dutch Health Council

Fellowship and Awards

  • ESHO award for life time achievement in hyperthermia

Research Output (291)

3-Dimensional target coverage assessment for MRI guided esophageal cancer radiotherapy

Boekhoff M. R., Defize I. L., Borggreve A. S., Takahashi N., van Lier A. L.H.M.W., Ruurda J. P., van Hillegersberg R., Lagendijk J. J.W., Mook S., Meijer G. J. 1 jun 2020, In: Radiotherapy and Oncology. 147 , p. 1-7 7 p.

DeepDose:Towards a fast dose calculation engine for radiation therapy using deep learning

Kontaxis C, Bol G H, Lagendijk J J W, Raaymakers B W 8 apr 2020, In: Physics in medicine and biology. 65 10 p.

Optimal timing for prediction of pathologic complete response to neoadjuvant chemoradiotherapy with diffusion-weighted MRI in patients with esophageal cancer

Borggreve Alicia S, Heethuis Sophie E, Boekhoff Mick R, Goense Lucas, van Rossum Peter S N, Brosens Lodewijk A A, van Lier Astrid L H M W, van Hillegersberg Richard, Lagendijk Jan J W, Mook Stella, Ruurda Jelle P, Meijer Gert J 1 apr 2020, In: European Radiology. 30 , p. 1896-1907 12 p.

Transceive phase mapping using the PLANET method and its application for conductivity mapping in the brain

Gavazzi Soraya, Shcherbakova Yulia, Bartels Lambertus W., Stalpers Lukas J.A., Lagendijk Jan J.W., Crezee Hans, van den Berg Cornelis A.T., van Lier Astrid L.H.M.W. feb 2020, In: Magnetic Resonance in Medicine. 83 , p. 590-607 18 p.

Preoperative prediction of pathologic response to neoadjuvant chemoradiotherapy in patients with esophageal cancer using 18F-FDG PET/CT and DW-MRI:a prospective multicenter study

Borggreve Alicia S, Goense Lucas, van Rossum Peter S N, Heethuis Sophie E, van Hillegersberg Richard, Lagendijk Jan J W, Lam Marnix G E H, van Lier Astrid L H M W, Mook Stella, Ruurda Jelle P, van Vulpen Marco, Voncken Francine E M, Aleman Berthe M P, Bartels-Rutten Annemarieke, Ma Jingfei, Fang Penny, Musall Benjamin C, Lin Steven H, Meijer Gert J 25 jan 2020, In: International Journal of Radiation Oncology Biology Physics. 106 , p. 998-1009 12 p.

Dosimetric impact of soft-tissue based intrafraction motion from 3D cine-MR in prostate SBRT

de Muinck Keizer D M, Kontaxis C, Kerkmeijer L G W, van der Voort van Zyp J R N, van den Berg C A T, Raaymakers B W, Lagendijk J J W, de Boer J C J 17 jan 2020, In: Physics in Medicine and Biology. 65 10 p.

The noise navigator:a surrogate for respiratory-correlated 4D-MRI for motion characterization in radiotherapy

Navest R J M, Mandija S, Bruijnen T, Stemkens B, Tijssen R H N, Andreychenko A, Lagendijk J J W, van den Berg C A T 13 jan 2020, In: Physics in medicine and biology. 65 9 p.

Soft-tissue prostate intrafraction motion tracking in 3D cine-MR for MR-guided radiotherapy

de Muinck Keizer Daan M, Kerkmeijer Linda G W, Maspero Matteo, Andreychenko Anna, van der Voort van Zyp Jochem R N, Van den Berg Cornelis A T, Raaymakers Bas W, Lagendijk Jan J W, de Boer J C J 5 dec 2019, In: Physics in Medicine and Biology. 64 , p. 235008 12 p.

The transformation of radiation oncology using real-time magnetic resonance guidance:A review

Hall William A., Paulson Eric S., van der Heide Uulke A., Fuller Clifton D., Raaymakers B. W., Lagendijk Jan J.W., Li X. Allen, Jaffray David A., Dawson Laura A., Erickson Beth, Verheij Marcel, Harrington Kevin J., Sahgal Arjun, Lee Percy, Parikh Parag J., Bassetti Michael F., Robinson Clifford G., Minsky Bruce D., Choudhury Ananya, Tersteeg Robert J.H.A., Schultz Christopher J., 1 nov 2019, In: European Journal of Cancer. 122 , p. 42-52 11 p.

A Coaxial RF Applicator for Ultra-High Field Human MRI

Solomakha Georgiy, Andreychenko Anna, van de Moortele Pierre-Francois, Kroeze H., Raaijmakers Alexander J., Euwe F. E., Lagendijk J. J. W., Luijten P. R., van den Berg C. A. T. okt 2019, In: IEEE Transactions on Biomedical Engineering. 66 , p. 2848-2854 7 p.

All Research Output (291)