prof. dr. J.H.H.M. (Janneke) van de Wijgert

Full Professor

  • Department of Epidemiology
  • Julius Center Research Program Infectious Diseases

prof. dr. J.H.H.M. (Janneke) van de Wijgert

Research Programs


Janneke van de Wijgert received a MSc in Biomedical Sciences from Utrecht University (1990), a Master in Public Health (1993) and PhD (1997) in Epidemiology from the University of California at Berkeley, and a MD degree from Utrecht University (2016; SUMMA program). She worked as a Research/Teaching Assistant and Postdoctoral Researcher at the University of California in San Franciscio (UCSF; 1991-1999; 5 years of which as Director of the UZ-UCSF Women’s Health Program in Harare, Zimbabwe), as Program Associate at the Population Council in New York (1999-2002), and as Assistant/Associate Professor at the Academic Medical Center, Amsterdam Institute for Global Health and Development, in Amsterdam (2003-2012). Between 1995 and 2004, she co-founded three clinical research centers in Africa. She was appointed Full Professor in the Institute of Infection and Global Health at the University of Liverpool in 2012 and in the Julius Center of the University Medical Center Utrecht in 2017. She currently still divides her time between Utrecht and Liverpool. She has supervised/is supervising multiple PhD, Master’s and Bachelor students, and has published more than 150 peer-reviewed papers.


Janneke van de Wijgert’s early research career was focused on HIV, and in particular the role of the cervicovaginal micro-environment in HIV transmission and clinical trials of HIV prevention interventions. She is now expanding her knowledge of the human microbiota and mucosal immunology to other health problems. Her current focus is the role of the human microbiota and immunology in reproductive and neonatal health more broadly, and in chronic inflammatory conditions (for example, within the Infection and Immunity theme of the UMCU). She incorporates ‘-omics’ and other complex biological data into clinical epidemiological models to study associations with clinical outcomes, as well as the effect of interventions.


Side Activities

    • Keystone Symposia, Chair of the Organizing Committee: Role of the Genital Tract Microbiome in Sexual and Reproductive Health;
    • Associate Editor ‘Microbiome’ and ‘AIDS’;
    • Regular peer reviewer for many other journals;
    • Regular grant reviewer;
    • Regular invited speaker, session chair, or Scientific Advisory Committee member at scientific meetings and conferences.

Research Output (55)

Human papillomavirus infection and cervical dysplasia in HIV-positive women:potential role of the vaginal microbiota

van de Wijgert Janneke H H M, Gill A Christina, Chikandiwa Admire, Verwijs Marijn C, Kelly Helen A, Omar Tanvier, Delany-Moretlwe Sinead, Segondy Michel, Francis Suzanna, Darby Alistair C, Mayaud Philippe, 1 jan 2020, In: AIDS. 34 , p. 115-125 11 p.

Lactobacilli-containing vaginal probiotics to cure or prevent bacterial or fungal vaginal dysbiosis:a systematic review and recommendations for future trial designs

van de Wijgert Jhhm, Verwijs M C 1 jan 2020, In: BJOG - An International Journal of Obstetrics and Gynaecology. 127 , p. 287-299 13 p.

Authors' reply re:Lactobacilli-containing vaginal probiotics to cure or prevent bacterial or fungal vaginal dysbiosis: a systematic review and recommendations for future trial designs

van de Wijgert Janneke Hhm, Verwijs Marijn C jan 2020, In: BJOG - An International Journal of Obstetrics and Gynaecology. 127 , p. 305 1 p.

Impact of oral metronidazole treatment on the vaginal microbiota and correlates of treatment failure

Verwijs Marijn C, Agaba Stephen K, Darby Alistair C, van de Wijgert Janneke H H M 9 aug 2019, In: American Journal of Obstetrics and Gynecology. 222 , p. 157.e1-157.e13 13 p.

Effects of an over-the-counter lactic-acid containing intra-vaginal douching product on the vaginal microbiota

van der Veer C, Bruisten S M, van Houdt R, Matser A A, Tachedjian G, van de Wijgert J H H M, de Vries H J C, van der Helm J J 25 jul 2019, In: BMC Microbiology [E]. 19

Targeted point-of-care testing compared with syndromic management of urogenital infections in women (WISH):a cross-sectional screening and diagnostic accuracy study

Verwijs Marijn C, Agaba Stephen K, Sumanyi Jean-Claude, Umulisa Marie Michele, Mwambarangwe Lambert, Musengamana Viateur, Uwineza Mireille, Cuylaerts Vicky, Crucitti Tania, Jespers Vicky, van de Wijgert Janneke H H M jun 2019, In: The Lancet Infectious Diseases. 19 , p. 658-669 12 p.

Implementation and evaluation of the Presto combined qualitative real-time assay for Chlamydia trachomatis and Neisseria gonorrhoeae in Rwanda

Cuylaerts Vicky, De Baetselier Irith, Muvunyi Claude M, Mwambarange Lambert, Smet Hilde, Rusine John, Musengamana Viateur, van de Wijgert Janneke, Crucitti Tania 18 apr 2019, In: African journal of laboratory medicine. 8 6 p.

The evolving facets of bacterial vaginosis:implications for HIV transmission

McKinnon Lyle R, Achilles Sharon, Bradshaw Catriona S, Burgener Adam, Crucitti Tania, Fredricks David N, Jaspan Heather B, Kaul Rupert, Kaushic Charu, Klatt Nichole, Kwon Douglas S, Marrazzo Jeanne M, Masson Lindi, McClelland Scott, Ravel Jacques, van de Wijgert Janneke H H M, Vodstrcil Lenka A, Tachedjian Gilda 14 jan 2019, In: AIDS Research and Human Retroviruses. 35 , p. 219-228 10 p.

Hormonal contraceptives and the acquisition of sexually transmitted infections:an updated systematic review

McCarthy Katharine J, Gollub Erica L, Ralph Lauren, van de Wijgert Janneke, Jones Heidi E 8 jan 2019, In: Sexually Transmitted Diseases. 46 , p. 290-296 7 p.

The Need for Policy Change Regarding Progestin-Only Injectable Contraceptives

Gollub Erica L, Jones Heidi E, Ralph Lauren J, van de Wijgert Janneke H H M, Padian Nancy, Stein Zena 21 dec 2018, In: Journal of Women's Health. 28 , p. 1180-1184 5 p.

All Research Output (55)