dr. ir. M. (Miguel) Dias Castilho


  • Department of Orthopaedics

dr. ir. M. (Miguel) Dias Castilho

Research Programs


Miguel Castilho is an Assistant Professor of Biofabrication at the Department of Orthopedics, University Medical Center Utrecht (UMCU) and a Guest Researcher at the Department of Biomedical Engineering, Eindhoven University of Technology (TU/e). His research focuses on manufacturing bio-inspired structural materials for musculoskeletal tissue engineering, in particular bone. A special focus lies on the integration of mechanotransduction concepts in biofabricated implants. At the UMCU, he personally leads the research efforts on the development of custom additive manufacturing systems for biomaterials processing and biofabrication. Dr. Castilho holds a MSc degree in Mechanical Engineering and a PhD in Biomedical engineering (with high distinction) from the Technical University of Lisbon (IST, Portugal). In addition, he was a visiting research scholar at the Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany, and at the Center for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, Portugal. For his contributions to the Biofabrication field he was awarded the Young investigator award from the Wake Forest Institute for Regenerative Medicine, USA.

Research Output (11)

Fiber Scaffold Patterning for Mending Hearts:3D Organization Bringing the Next Step

Kristen Marleen, Ainsworth Madison J., Chirico Nino, van der Ven Casper F.T., Doevendans Pieter A., Sluijter Joost P.G., Malda Jos, van Mil Alain, Castilho Miguel 11 okt 2019, In: Advanced Healthcare Materials. 9 21 p.

Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration

Castilho Miguel, Mouser Vivian, Chen Mike, Malda Jos, Ito Keita 22 jun 2019, In: Acta Biomaterialia. 95 , p. 297-306 10 p.

Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds

Jansen Katja, Castilho Miguel, Aarts Sanne, Kaminski Michael M, Lienkamp Soeren S, Pichler Roman, Malda Jos, Vermonden Tina, Jansen Jitske, Masereeuw Rosalinde feb 2019, In: Macromolecular Bioscience. 19

Simultaneous Micropatterning of Fibrous Meshes and Bioinks for the Fabrication of Living Tissue Constructs

de Ruijter Mylène, Ribeiro Alexandre, Dokter Inge, Castilho Miguel, Malda Jos 17 jun 2018, In: Advanced Healthcare Materials. 8

Mechanical behavior of a soft hydrogel reinforced with three-dimensional printed microfibre scaffolds

Castilho Miguel, Hochleitner Gernot, Wilson Wouter, van Rietbergen Bert, Dalton Paul D., Groll Jürgen, Malda Jos, Ito Keita 19 jan 2018, In: Scientific Reports. 8 , p. 1245

Melt Electrowriting Allows Tailored Microstructural and Mechanical Design of Scaffolds to Advance Functional Human Myocardial Tissue Formation

Castilho Miguel, van Mil Alain, Maher Malachy, Metz Corina H.G., Hochleitner Gernot, Groll Jürgen, Doevendans Pieter A., Ito Keita, Sluijter Joost P.G., Malda Jos 1 jan 2018, In: Advanced Functional Materials. 28 10 p.

Bio-resin for high resolution lithography-based biofabrication of complex cell-laden constructs

Levato Riccardo, Costa Pedro F, Castilho Miguel D, Alcala-Orozco Cesar R, van Dorenmalen Kim M A, Melchels Ferry P W, Gawlitta Debby, Hooper Gary J, Malda Jos, Woodfield Tim B F 2018, In: Biofabrication. 10 , p. 034101

Assessing bioink shape fidelity to aid material development in 3D bioprinting

Ribeiro A., Blokzijl M. M., Levato R., Visser C. W., Castilho M., Hennink W. E., Vermonden T., Malda J. 30 nov 2017, In: Biofabrication. 10

Fixation of Hydrogel Constructs for Cartilage Repair in the Equine Model:A Challenging Issue

Mancini Irina A.D., Vindas Bolaños Rafael A., Brommer Harold, Castilho Miguel, Ribeiro Alexandro, Van Loon Johannes P.A.M., Mensinga Anneloes, Van Rijen Mattie H.P., Malda Jos, van Weeren P. René 1 nov 2017, In: Tissue engineering. Part C, Methods. 23 , p. 804-814 11 p.

Melt Electrospinning Writing of Poly-Hydroxymethylglycolide-co-ε-Caprolactone-Based Scaffolds for Cardiac Tissue Engineering

Castilho Miguel, Feyen Dries, Flandes-Iparraguirre María, Hochleitner Gernot, Groll Jürgen, Doevendans Pieter A.F., Vermonden Tina, Ito Keita, Sluijter Joost P.G., Malda Jos sep 2017, In: Advanced Healthcare Materials. 6

All Research Output (11)