Wij zijn onze website aan het vernieuwen.

Ontdekt u nog een pagina die niet klopt of hebt u een goede suggestie, laat het ons dan weten via webmedia@umcutrecht.nl.

Deze website maakt gebruik van cookies

Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Lees meer over het cookiebeleid.

prof. dr. D.E. Grobbee Full Professor

  • Department of Epidemiology
  • Julius Center Research Program Cardiovascular Epidemiology

D.E. Grobbee


Research Programs


Biographical Sketch

Diederick (Rick) E. Grobbee was trained as a medical doctor at Utrecht University. He then conducted PhD research in the field of hypertension at Erasmus University in Rotterdam (12/83-6/1986). After a residency in Internal Medicine, he returned to the Erasmus University as an associate professor and then Full professor of Clinical Epidemiology (1993). In Rotterdam he was responsible for the cardiovascular disease research program of the Department of Epidemiology, and was one of the founders of the Rotterdam Study (www.epib.nl/research/ergo.htm). In 1996 he was appointed professor of Clinical Epidemiology at Utrecht University and founded of the Julius Center for Health Sciences and Primary Care (1996), a division of the University Medical Center Utrecht (UMCU) currently employing approximately 500 staff (www.juliuscenter.nl). In 2008 he founded Julius Clinical Ltd., a full service Academic Clinical Research Organization (www.juliusclinical.com) of which he serves as Chief Medical Officer and Statutory Director. At the University Medical Center Utrecht, he just finished his term as the chair of the Center for Circulatory Health at the UMCU governing cardiovascular patient care, research and education. Previous positions include director of the Rotterdam Medical Research Foundation, member of the board of Erasmus University Medical Center, and visiting Associate Professor at Harvard University, Boston. He holds honorary appointments in Sydney and Kuala Lumpur.  At Utrecht University he was appointed Distinguished University Professor in 2010.

Rick Grobbee has been a (principal) investigator in many large-scale epidemiologic studies and randomized intervention trials relating to the prevention and treatment of cardiovascular, cardiometabolic, and cardiorenal disease. In addition he works on the principles and methods of treatment research, trial design and (big-) data analysis. In the Netherlands he was member of the supervisory board of the Netherlands Heart Foundation and acted in several roles in committees of the National Research Council (ZonMW). He is chair of the Dutch National Research Agenda (NWA) route "Prevention". He has been listed in the top 100 global most influential biomedical researchers (Eur J Clin Invest 2013 Dec;43(12):1339-65) and has consistently been ranked as highly cited author by Web of Science over the last decades.

Rick Grobbee has been on the editorial boards of several journals and (inter) national scientific, search, and site-visit committees. Current journal roles include editor-in-chief of Global Heart (https://globalheartjournal.com/), senior consulting editor of the European Journal of Preventive Cardiology of which he served as editor-in-chief for eight years. He is immediate past-president of the European Association for Preventive Cardiology and member of the board of the European Society of Cardiology (ESC) and chair of the ESC Global Affairs Committee. He is member of the board of the World Heart Federation Rick Grobbee is fellow of the Royal Dutch Academy of Sciences and served as the chair of its Medical Section and Advisory Council for the Medical Sciences. He is honorary fellow of the Indonesian Heart Association and of the Romanian Society of Cardiology.  In recent years his attention has increasingly been directed towards global circulatory health (www.globalhealth.eu ), and on-line education for which he founded Elevate, a platform providing global post graduate courses, masters programs and eductional consultancy (www.elevatehealth.eu ).  Rick Grobbee was a recipient of a 2019 NWO Gravitation Award "Exposomics" and current coordinator of three EU grants. In 2017 he was knighted by the Dutch King (Knight in the Order of the Dutch Lion). To date, Prof. Grobbee has authored or co-authored over 1,300 scientific papers (PubMed), chapters, and books, and has supervised more than 150 PhD fellows. His Hirsch index (Web of Science) is 151.


Side Activities


    • Chief Scientific Officer and Statutory Director, Julius Clinical Ltd. Academic Clinical Research Organization (0.5 Fte)
    • Director, Utrecht University MSc and PhD in Epidemiology Programmes
    • Chair ("Boegbeeld"), National Research Agenda (NWA) Route Health Research, Prevention and Treatment
    • Member, Board of Studies, Graduate School Life Sciences, Utrecht University
    • Fellow, Royal Dutch Academy of Sciences
    • Fellow, European Society of Cardiology
    • Member, Board, European Society of Cardiology
    • Member, Board, World Heart Federation
    • Chair, Global Affairs Committee, European Society of Cardiology
    • Member, Practice Guidelines Committee, European Society of Cardiology
    • Past-President, European Association for Cardiovascular Prevention and Rehabilitation
    • Member Executive Board, European Association for Cardiovascular Prevention and Rehabilitation
    • Chair, International Scientific Advisory Board, BBMRI (Biobanking Netherlands)
    • Editor in Chief, Global Heart
    • Senior Consulting Editor, European Journal of Cardiovascular Prevention and Rehabilitation
    • Member, Editorial Board Netherlands Journal of Medicine
    • Member, Editorial Board, Current Cardiovascular Risk Reports
    • Member, Editorial Board Cardiovascular Risk
    • Member, Various Scientific Advisory, Safety Monitoring en Adjudication Committees International Clinical Trials


Fellowship and Awards

    • 2008 Prevention award. German Society of Cardiology
    • 2008 Catharijne Prize
    • 2009 David de Wied lecture
    • 2009 Fellow of the Netherlands Royal Academy of Sciences
    • 2010 Distinguished University Professor of International Health Sciences and Global Health, Utrecht University
    • 2016 Honorary Fellow, Indonesian Heart Association
    • 2016 Romanian Society of Cardiology
    • 2017 Knight. Order of the Dutch Lion

Research Output (1037)

Corrigendum to “2019 ESC/EAS Guidelines for the management of dyslipidaemias:lipid modification to reduce cardiovascular risk” (Atherosclerosis (2019) 290 (140–205), (S0021915019314595), (10.1016/j.atherosclerosis.2019.08.014))

Mach Francois, Baigent Colin, Catapano Alberico L., Koskinas Konstantinos C., Casula Manuela, Badimon Lina, Chapman M. John, De Backer Guy G., Delgado Victoria, Ference Brian A., Graham Ian M., Halliday Alison, Landmesser Ulf, Mihaylova Borislava, Pedersen Terje R., Riccardi Gabriele, Richter Dimitrios J., Sabatine Marc S., Taskinen Marja Riitta, Tokgozoglu Lale, Wiklund Olov, Nibouche Djamaleddine, Zelveian Parounak H., Siostrzonek Peter, Najafov Ruslan, van de Borne Philippe, Pojskic Belma, Postadzhiyan Arman, Kypris Lambros, Špinar Jindřich, Larsen Mogens Lytken, Eldin Hesham Salah, Viigimaa Margus, Strandberg Timo E., Ferrieres Jean, Agladze Rusudan, Laufs Ulrich, Rallidis Loukianos, Bajnok Laszlo, Gudjonsson Thorbjorn, Maher Vincent, Henkin Yaakov, Gulizia Michele Massimo, Mussagaliyeva Aisulu, Bajraktari Gani, Kerimkulova Alina, Latkovskis Gustavs, Hamoui Omar, Visseren Frank, Grobbee Diederick, , , 1 feb 2020, In: Atherosclerosis. 294 , p. 80-82 3 p.

Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes:An analysis of the AleCardio trial

Koomen Jeroen V, Heerspink Hiddo J L, Schrieks Ilse C, Schwartz Gregory G, Lincoff A Michael, Nicholls Stephen J, Svensson Anders, Wedel Hans, Weichert Arlette, Grobbee Diederick E, Stevens Jasper jan 2020, In: Diabetes, Obesity & Metabolism. 22 , p. 30-38 9 p.

Cardiovascular disease risk in an urban African population:a cross-sectional analysis on the role of HIV and antiretroviral treatment

Vos Alinda G, Hoeve Klariska, Barth Roos E, Peper Joyce, Moorhouse Michelle, Crowther Nigel J, Venter Willem D F, Grobbee Diederick E, Bots Michiel L, Klipstein-Grobusch Kerstin 3 dec 2019, In: Retrovirology. 16 10 p.

Urinary Ethyl Glucuronide Can Be Used as a Biomarker of Habitual Alcohol Consumption in the General Population

van de Luitgaarden Inge A.T., Beulens Joline W.J., Schrieks Ilse C., Kieneker Lyanne M., Touw Daan J., van Ballegooijen Adriana J., van Oort Sabine, Grobbee Diederick E., Bakker Stephan J.L. 1 dec 2019, In: The Journal of nutrition. 149 , p. 2199-2205 7 p.

Global Capacity Building for Global Challenges in Cardiovascular Disease

Grobbee Diederick E 1 dec 2019, In: Global heart. 14 , p. 345-346 2 p.

Cardiovascular guidelines based on high-quality evidence:Are we getting there?

van Dijk Wouter B, Grobbee Diederick E 1 dec 2019, In: European Journal of Preventive Cardiology. 26 , p. 1915-1917 3 p.

Effects of HIV Infection on Pulmonary Artery Pressure in Children

Idris Nikmah S, Uiterwaal Cuno S P M, Burgner David P, Grobbee Diederick E, Kurniati Nia, Cheung Michael M H dec 2019, In: Global heart. 14 , p. 367-372 6 p.

The moral and legal status of Health Care Workers in Cluster Randomized Trials:a response to Weijer and Taljaard

van der Graaf Rieke, van Thiel Ghislaine J.M.W., de Hoop Esther Oomen, Moons Karel G.M., Grobbee Diederick E., van Delden Johannes J.M. dec 2019, In: Journal of Clinical Epidemiology. 116 , p. 146-149 4 p.

Immunogenicity and Safety of an Early Measles Vaccination Schedule at 6 and 12 Months of Age in Human Immunodeficiency Virus (HIV)-Unexposed and HIV-Exposed, Uninfected South African Children

Mutsaerts Eleonora A.M.L., Nunes Marta C., Bhikha Sutika, Ikulinda Benit T., Boyce Welekazi, Jose Lisa, Koen Anthonet, Moultrie Andrew, Cutland Clare L., Grobbee Diederick E., Klipstein-Grobusch Kerstin, Madhi Shabir A. 1 nov 2019, In: The Journal of infectious diseases. 220 , p. 1529-1538 10 p.

The effect of an mhealth clinical decision-making support system on neonatal mortality in Ghana

Amoakoh H. B., Klipstein-Grobusch K., Agyepong I. A., Zuithoff P., Amoakoh-Coleman M., Kayode G. A., Sarpong C., Reitsma J. B., Grobbee D. E., Ansah E. K. nov 2019, In: European Journal of Public Health. 29

All Research Output (1037)
To top