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prof. dr. A.D.R. (Alwin) Huitema Full Professor

  • Clinical Pharmacy

A.D.R. Huitema

Contact

Research Programs

Side Activities

  • 2002 - : Member of the Medical Ethical Committee of Netherlands Cancer Institute

    2003 - : Involved in many early clinical trials of novel anticancer agents (not further specified, revenues for Netherlands Cancer Institute)

    2016 - 2018: Member of scientific councel "Stichting Kinderen Kankervrij (KiKa)"

    2017 - : Member of the working group Oncology & Hematology of "Horizonscan geneesmiddelen", ZorgInstituut Nederland

    2018 - : Board member of Dutch Society of Clinical Pharmacology & Biopharmaceutics

Fellowship and Awards

  • 2015 Galenus research prize

    2014 Huizinga penning of the Dutch Association of Hospital Pharmacists

Research Output (134)

Quantification of T Cell Binding Polyclonal Rabbit Anti-thymocyte Globulin in Human Plasma with Liquid Chromatography Tandem-Mass Spectrometry

Amrani Mohsin El, Admiraal Rick, Willaert Lobke, Ebskamp-van Raaij Lysette J C, Lacna Amelia M, Hack C Erik, Huitema Alwin D R, Nierkens Stefan, van Maarseveen Erik M 1 mrt 2020, In: AAPS Journal. 22 8 p.

A Population Pharmacokinetic Model of Oral Docetaxel Coadministered With Ritonavir to Support Early Clinical Development

Yu Huixin, Janssen Julie M, Sawicki Emilia, van Hasselt J G Coen, de Weger Vincent A, Nuijen Bastiaan, Schellens Jan H M, Beijnen Jos H, Huitema Alwin D R mrt 2020, In: Journal of Clinical Pharmacology. 60 , p. 340-350 11 p.

Exposure to Docetaxel in the Elderly Patient Population:a Population Pharmacokinetic Study

Crombag Marie-Rose B S, Dorlo Thomas P C, van der Pan Ellen, van Straten Anoek, Bergman Andries M, van Erp Nielka P, Beijnen Jos H, Huitema Alwin D R 1 dec 2019, In: Pharmaceutical Research. 36

Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?

Crombag Marie-Rose B S, Koolen Stijn L W, Wijngaard Sophie, Joerger Markus, Dorlo Thomas P C, van Erp Nielka P, Mathijssen Ron H J, Beijnen Jos H, Huitema Alwin D R 1 dec 2019, In: Pharmaceutical Research. 36

Sialic Acid-Engineered IL4-10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation

Steen-Louws Cristine, Boross Peter, Prado Judith, Meeldijk Jan, Langenhorst Jurgen B, Huitema Alwin D R, den Hartog Marcel T, Boon Louis, Lafeber Floris P J G, Hack C Erik, Eijkelkamp Niels, Popov-Celeketic Jelena dec 2019, In: Pharmaceutical Research. 37

High Variability of Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

Sikma Maaike A, Hunault Claudine C, Van Maarseveen Erik M, Huitema Alwin D R, Van de Graaf Ed A, Kirkels Johannes H, Verhaar Marianne C, Grutters Jan C, Kesecioglu Jozef, De Lange Dylan W 19 nov 2019, In: European journal of drug metabolism and pharmacokinetics. 45 , p. 123-134 12 p.

Six-step workflow for the quantification of therapeutic monoclonal antibodies in biological matrices with liquid chromatography mass spectrometry - A tutorial

El Amrani Mohsin, Donners Anouk A.M., Hack C. Erik, Huitema Alwin D.R., van Maarseveen Erik M. 8 nov 2019, In: Analytica Chimica Acta. 1080 , p. 22-34 13 p.

Pharmacokinetics of capecitabine and four metabolites in a heterogeneous population of cancer patients:a comprehensive analysis

Jacobs Bart A W, Deenen Maarten J, Joerger Markus, Rosing Hilde, de Vries Niels, Meulendijks Didier, Cats Annemieke, Beijnen Jos H, Schellens Jan H M, Huitema Alwin D R 25 okt 2019, In: CPT: Pharmacometrics and Systems Pharmacology. 8 , p. 940-950 11 p.

Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer

van Nuland Merel, Bergman Andries M, Rosing Hilde, de Vries Niels, Huitema Alwin D R, Beijnen Jos H 9 okt 2019, In: Pharmacotherapy. 39 , p. 1137-1145 9 p.

Therapeutic Drug Monitoring of Oral Anticancer Drugs:The Dutch Pharmacology Oncology Group-Therapeutic Drug Monitoring Protocol for a Prospective Study

Groenland Stefanie L, van Eerden Ruben A G, Verheijen Remy B, Koolen Stijn L W, Moes Dirk Jan A R, Desar Ingrid M E, Reyners Anna K L, Gelderblom Hans J, van Erp Nielka P, Mathijssen Ron H J, Huitema Alwin D R, Steeghs Neeltje okt 2019, In: Therapeutic Drug Monitoring. 41 , p. 561-567 7 p.

All Research Output (134)
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