Linde Meyaard

Full Professor

Strategic program(s):

Biography

Linde Meyaard obtained her PhD in 1995 (cum laude) at Sanquin in Amsterdam studying mechanism of immune dysfunction in HIV infection. In 1996 she entered the immune inhibitory receptor field as a post-doc at DNAX Research Institute in California. She identified a novel inhibitory immune receptor, LAIR-1, and continued her work on this receptor in as a fellow of the Royal Academy of Sciences (KNAW) in the UMC Utrecht.

Since 2000 she leads her own research group embedded in the Center Translational Immunology, supported by multiple grants such as the NWO Vidi and Vici. Meyaard was the first to identify collagens and collagen-like proteins as the natural ligands for LAIR-1. She then extended her research towards other inhibitory receptors and studies these inhibitory receptors in...

Strategic program(s):

Contact

lmeyaard@umcutrecht.nl

Pure profile

Research groups

Inhibitory receptor lab

Research aim

To use the full potential of inhibitory receptors to cure inflammatory disease and cancer

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Recent publications

All publications

A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets Akashdip Singh, Alberto Miranda Bedate, Helen J von Richthofen, Saskia V Vijver, Michiel van der Vlist, Raphael Kuhn, Alexander Yermanos, Jürgen J Kuball, Can Kesmir, M Ines Pascoal Ramos, Linde Meyaard
eLife, 2024, vol. 13

Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis Tiago Carvalheiro, Wioleta Marut, M. Inês Pascoal Ramos, Samuel García, Devan Fleury, Alsya J. Affandi, Aniek S. Meijers, Barbara Giovannone, Ralph G. Tieland, Eline Elshof, Andrea Ottria, Marta Cossu, Matthew L. Meizlish, Tineke Veenendaal, Meera Ramanujam, Miguel E. Moreno-García, Judith Klumperman, Nalan Liv, Timothy R.D.J. Radstake, Linde Meyaard
... Show all

Angiogenic factors and the lectin pathway of complement in women with secondary recurrent pregnancy loss M. C. Krog, E. M. Flachs, A. M. Kolte, W. de Jager, L. Meyaard, O. B. Christiansen, R. Steffensen, K. Vomstein, P. Garred, H. S. Nielsen
Journal of Reproductive Immunology, 2024, vol. 163, p.1-8

Mechanosensing regulates tissue repair program in macrophages Matthew L. Meizlish, Yoshitaka Kimura, Scott D. Pope, Rita Matta, Catherine Kim, Naomi H. Philip, Linde Meyaard, Anjelica Gonzalez, Ruslan Medzhitov
Science advances, 2024, vol. 10

Understanding the matrix Rowie Borst, Linde Meyaard, M. Ines Pascoal Ramos
Journal of Translational Medicine, 2024, vol. 22

Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice Akashdip Singh, Eline T A M Mommers-Elshof, Saskia V Vijver, J H Marco Jansen, Susanne Gonder, Robert Jan Lebbink, Dominique Bihan, Richard W Farndale, Louis Boon, Solomon Langermann, Jeanette H W Leusen, Dallas Flies, Linde Meyaard, M Ines Pascoal Ramos
Cancer Immunology, Immunotherapy, 2024, vol. 73

Fellowships & Awards

1999-2001 Fellow of the Royal Dutch Academy of Science (KNAW)

2001 NWO Vidi

2002 NWO Aspasia

2014 NWO Vici

External positions

Consultant - Consulteren op het gebied van immunology - AbbVie

Member of the review committee - review public-private funding (PPS) submissions - Dutch Cancer Society (KWF)

Investigator - dezelfde werkzaamheden als huidige functie - Oncode

Collaborative research agreement - Ik werk samen...