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dr. V. (Victor) Peperzak Assistant Professor

  • Laboratory for Translational Immunology (LTI)

V. Peperzak


Research Programs

Research Output (11)

Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting

Slomp Anne, Moesbergen Laura M, Gong Jia-Nan, Cuenca Marta, von dem Borne Peter A, Sonneveld Pieter, Huang David C S, Minnema Monique C, Peperzak Victor 23 dec 2019, In: Blood Advances. 3 , p. 4202-4214 13 p.

Dexamethasone synergizes with MCL-1 inhibition in multiple myeloma through suppression of S6 phosphorylation

Spaan Ingrid, Timmerman Laura, Kimman Thoman, Slomp Anne, Cuenca Marta, Minnema Monique, Raymakers Reinier, Peperzak Victor okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E110-E110

Multiple myeloma with amplification of chromosome 1q is highly sensitive to MCL-1 targeting

Slomp Anne, Moesbergen Laura, Gong Jia-nan, Cuenca Marta, Borne Peter von dem, Sonneveld Pieter, Huang David, Minnema Monique, Peperzak Victor okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E49-E50

A Highly Reproducible 3D Culture Approach for Functional Drug Testing on Primary Multiple Myeloma Cells.

Peperzak Victor, Cuenca Marta, Moesbergen Laura, van Nieuwenhuijzen Niels, Slomp Anne, Minnema Monique okt 2019, In: Clinical Lymphoma, Myeloma and Leukemia. 19 , p. E97-E97

MCL-1 Inhibition Is Highly Effective Against Multiple Myeloma Cells from Poor Prognosis Patients

Slomp Anne, Moesbergen Laura M., Halkes Constantijn J. M., Sonneveld Pieter, Minnema Monique C., Peperzak Victor 29 nov 2018, In: Blood. 132 , p. 1916

From MGUS to Multiple Myeloma, a Paradigm for Clonal Evolution of Premalignant Cells

van Nieuwenhuijzen Niels, Spaan Ingrid, Raymakers Reinier, Peperzak Victor 15 mei 2018, In: Cancer Research. 78 , p. 2449-2456 8 p.

Wnt signaling in multiple myeloma:a central player in disease with therapeutic potential

Spaan Ingrid, Raymakers Reinier A, van de Stolpe Anja, Peperzak Victor 2018, In: Journal of hematology & oncology. 11

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Vikström Ingela B, Slomp Anne, Carrington Emma M, Moesbergen Laura M, Chang Catherine, Kelly Gemma L, Glaser Stefan P, Jansen J H Marco, Leusen Jeanette H W, Strasser Andreas, Huang David C S, Lew Andrew M, Peperzak Victor, Tarlinton David M 2016, In: Cell death & disease. 7

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma

Middendorp Sabine, Xiao Yanling, Song Ji-Ying, Peperzak Victor, Krijger Peter H. L., Jacobs Heinz, Borst Jannie 10 sep 2009, In: Blood. 114 , p. 2280-2289 10 p.

Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation

Kim YM, Pan JYJ, Korbel GA, Peperzak Victor, Boes M, Ploegh HL 28 feb 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103 , p. 3327-3332 6 p.

All Research Output (11)
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