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prof. dr. A.B.J. (Berent ) Prakken

Full Professor

  • Immunology patient care

prof. dr. A.B.J. (Berent ) Prakken

Biography

Berent Prakken (MD, PhD) is vice-dean and director of the biomedical education centre at the Utrecht Medical Center Utrecht (UMCU), the Netherlands. He is also professor of pediatric immunology at the UMCU and honorary professor at the University of Ghent, Belgium. Berent Prakken has built a translational research lab that focused on regulation of inflammation and biomarker development in human in inflammatory diseases. He received numerous national and international awards and grants for his work. The work of his group is published in all major international journals, including Nature Medicine, PNAS, Immunity, the Lancet, JCI and in various Nature journals. Over the years he successfully mentored more than 40 PhD students. Prakken serves in various national and international research advisory boards and was member of the Dutch National Health Council (‘Gezondheidsraad’).  He was vice-chair of Medical Ethical Review Board (IRB) of the UMCU. Berent Prakken is president of the Pediatric Rheumatology European Society (PRES) and member of the EULAR executive committee. He is member of the steering committee of UCAN (international federation facilitating biological research in arthritis) and has set up the first international platform for biological studies in arthritis (UCAN-U, www.ucan-u.org). Berent Prakken’s personal commitment is to training & education and to improve the impact of science. Unconventional thinking, collaboration and crossing boundaries inspire him.

 

Side Activities

  • International profile (current positions)

    • President of the Pediatric Rheumatology European Society (PRES, http://www.pres.eu)

    • Member of the EULAR executive committee (http://www.eular.org)

    • Scientific director of the Eureka Institute (www.eurekainstitute.org).

    • Steering committee of UCAN (http://ucanetwork.com)

    • Founder and Chair of the first international platform for biological studies in arthritis (UCAN-U, www.ucan-u.org)

    • Coordinator of EUTRAIN (see above) and partner in EU FP7 projects MIAMI, MD-Pedigree; TREAT-AID and PHARMACHILD

    • Scientific Advisory Board Center for Therapeutic Target validation (CTTV; https://www.targetvalidation.org)

    • Scientific Advisory Board SAFE-PEDRUG project Vlaams Agentschap Innoveren en Ondernemen

    • Scientific Advisory Board Manchester MSK BRU National Institute for Health Research

    • Scientific Advisory Board FOREUM Foundation for Research in Rheumatology

     

     

    Scientific Profile

    • Co-chair of the clinical section of the Laboratory of Translational Immunology, UMCU

    • Co-chair of translational research group in pediatric inflammatory diseases (±15 FTE)

    • Executive committee of the focus area’s Child Health and Infection & Immunity.

    • Recipient of various prestigious national and international honorary lectures, awards and grants including VENI and VIDI awards for BP and his lab members

    • Chair of international core facility for biomarkers and the luminex technology (Including past core for Immune Tolerance Network of the NIH)

    • Regular invited speaker at major international scientific meetings

    • Associate editor of the Annals of Rheumatic Diseases (nr 1 journal in Rheumatology; IF 12.4)

    • Author of over 200 articles[1] in international journals, including Nature Medicine, Lancet, PNAS, J Exp Med, Immunity and JCI

    • Promotor of 51 PhD students

    • Vice-chair of the Institutional Ethics Review Board (2013-2015)

    • Acting Dean University Medical Center Utrecht (2019)


    [1] H-index 47 (> 8000 citations, mean > 40 citations per article)

Fellowship and Awards

  • 2016 - Dunlop Dottridge lecture, Canadian Rheumatology Association

    2013 - Abe Shore lecture, University of Toronto

    2005 - Jonxis penning and lecture University Medical Centre Groningen

    2003 - Ter Meulen Lecture Dutch Society of Paediatrics

    2001 - Kourir Award (European Society For Paediatric Rheumatology)

    1997 - Young Investigators Award Dutch Society of Paediatrics

    1996 - Cum Laude Thesis (University of Utrecht)

Research Output (330)

Critical Gaps in Understanding the Clinician-Scientist Workforce:Results of an International Expert Meeting

Weggemans Margot M., Friesen Farah, Kluijtmans Manon, Prakken Berent, Ten Cate Olle, Woods Nicole N., Rosenblum Norman D., 1 okt 2019, In: Academic medicine : journal of the Association of American Medical Colleges. 94 , p. 1448-1454 7 p.

How a four-year-old boy connects healthcare, biomedical research and undergraduate education

Drost Rijkent H., Dictus Wim J.A.G., Prakken Berent J., Bovenschen Niels 1 sep 2019, In: Nature Biotechnology. 37 , p. 1092-1095 4 p.

Children and young people get rheumatic disease too

Egert Yona, Egert Tsipi, Costello Wendy, Prakken Berent J., Smith Eve M.D., Wulffraat Nico M. 1 jan 2019, In: The Lancet. Child & adolescent health. 3 , p. 8-9 2 p.

Microbiome Analytics of the Gut Microbiota in Patients With Juvenile Idiopathic Arthritis:A Longitudinal Observational Cohort Study

van Dijkhuizen E. H.Pieter, Del Chierico Federica, Malattia Clara, Russo Alessandra, Pires Marafon Denise, ter Haar Nienke M., Magni-Manzoni Silvia, Vastert Sebastiaan J., Dallapiccola Bruno, Prakken Berent, Martini Alberto, De Benedetti Fabrizio, Putignani Lorenza, 28 dec 2018, In: Arthritis & Rheumatology. 71 , p. 1000-1010 11 p.

PD-1<sup>+</sup>CD8<sup>+</sup> T cells are clonally expanding effectors in human chronic inflammation

Petrelli Alessandra, Mijnheer Gerdien, Hoytema Van Konijnenburg David P., Van Der Wal Maria M., Giovannone Barbara, Mocholi Enric, Vazirpanah Nadia, Broen Jasper C., Hijnen Dirkjan, Oldenburg Bas, Coffer Paul J., Vastert Sebastian J., Prakken Berent J., Spierings Eric, Pandit Aridaman, Mokry Michal, Van Wijk Femke 1 okt 2018, In: Journal of Clinical Investigation. 128 , p. 4669-4681 13 p.

Effect of anticoagulants on 162 circulating immune related proteins in healthy subjects

Scholman Rianne C, Giovannone Barbara, Hiddingh Sanne, Meerding Jenny M, Malvar Fernandez Beatriz, van Dijk Mariska E A, Tempelman Mariëlle J, Prakken Berent J, de Jager Wilco jun 2018, In: Cytokine. 106 , p. 114-124 11 p.

Recommendations for collaborative paediatric research including biobanking in Europe:a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative

Kuemmerle-Deschner Jasmin B., Hansmann Sandra, Wulffraat Nico M., Vastert Sebastiaan J., Hens Kristien, Anton Jordi, Avcin Tadej, Martini Alberto, Koné-Paut Isabelle, Uziel Yosef, Ravelli Angelo, Wouters Carine, Shaw David, Özen Seza, Eikelberg Andreas, Prakken Berent J., Ruperto Nicolino, Horneff Gerd, Constantin Tamas, Beresford Michael W., Sikken Marijn, Foster Helen E., Haug Iris, Schuller Sabrina, Jägle Christine, Benseler Susanne M. 1 mrt 2018, In: Annals of the Rheumatic Diseases. 77 , p. 319-327 9 p.

Preventing translational scientists from extinction:The long-term impact of a personalized training program in translational medicine on the careers of translational scientists

Weggemans Margot M., van der Schaaf Marieke, Kluijtmans Manon, Hafler Janet P., Rosenblum Norman D., Prakken Berent J. 1 jan 2018, In: Frontiers in medicine. 5

Monocyte gene expression in childhood obesity is associated with obesity and complexity of atherosclerosis in adults

Keustermans G. C., Kofink D., Eikendal A., De Jager W., Meerding J., Nuboer R., Waltenberger J., Kraaijeveld A. O., Jukema J. W., Sels J. W., Garssen J., Prakken B. J., Asselbergs F. W., Kalkhoven E., Hoefer I. E., Pasterkamp G., Schipper H. S. 1 dec 2017, In: Scientific Reports. 7

Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children

Keustermans Genoveva, Van Der Heijden Laila B., Boer Berlinda, Scholman Rianne, Nuboer Roos, Pasterkamp Gerard, Prakken Berent, De Jager Wilco, Kalkhoven Eric, Janse Arieke J, Schipper Henk S. 1 okt 2017, In: PLoS ONE [E]. 12

All Research Output (330)