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dr. H.J.G. Snippert

Associate Professor

  • Group Snippert, section Molecular Cancer Research

Research Programs

Research Output (33)

Snake Venom Gland Organoids

Post Yorick, Puschhof Jens, Beumer Joep, Kerkkamp Harald M., de Bakker Merijn A.G., Slagboom Julien, de Barbanson Buys, Wevers Nienke R., Spijkers Xandor M., Olivier Thomas, Kazandjian Taline D., Ainsworth Stuart, Iglesias Carmen Lopez, van de Wetering Willine J., Heinz Maria C., van Ineveld Ravian L., van Kleef Regina G.D.M., Begthel Harry, Korving Jeroen, Bar-Ephraim Yotam E., Getreuer Walter, Rios Anne C., Westerink Remco H.S., Snippert Hugo J.G., van Oudenaarden Alexander, Peters Peter J., Vonk Freek J., Kool Jeroen, Richardson Michael K., Casewell Nicholas R., Clevers Hans 23 jan 2020, In: Cell. 180 , p. 233-247.e21

High-resolution 3D imaging of fixed and cleared organoids

Dekkers Johanna F., Alieva Maria, Wellens Lianne M., Ariese Hendrikus C.R., Jamieson Paul R., Vonk Annelotte M., Amatngalim Gimano D., Hu Huili, Oost Koen C., Snippert Hugo J.G., Beekman Jeffrey M., Wehrens Ellen J., Visvader Jane E., Clevers Hans, Rios Anne C. 1 jun 2019, In: Nature Protocols. 14 , p. 1756-1771 16 p.

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper Oded, de Witte Chris J, Lõhmussaar Kadi, Valle-Inclan Jose Espejo, Hami Nizar, Kester Lennart, Balgobind Anjali Vanita, Korving Jeroen, Proost Natalie, Begthel Harry, van Wijk Lise M, Revilla Sonia Aristín, Theeuwsen Rebecca, van de Ven Marieke, van Roosmalen Markus J, Ponsioen Bas, Ho Victor W H, Neel Benjamin G, Bosse Tjalling, Gaarenstroom Katja N, Vrieling Harry, Vreeswijk Maaike P G, van Diest Paul J, Witteveen Petronella O, Jonges Trudy, Bos Johannes L, van Oudenaarden Alexander, Zweemer Ronald P, Snippert Hugo J G, Kloosterman Wigard P, Clevers Hans mei 2019, In: Nature Medicine. 25 , p. 838-849 12 p.

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

Bolhaqueiro Ana C F, Ponsioen Bas, Bakker Bjorn, Klaasen Sjoerd J, Kucukkose Emre, van Jaarsveld Richard H, Vivié Judith, Verlaan-Klink Ingrid, Hami Nizar, Spierings Diana C J, Sasaki Nobuo, Dutta Devanjali, Boj Sylvia F, Vries Robert G J, Lansdorp Peter M, van de Wetering Marc, van Oudenaarden Alexander, Clevers Hans, Kranenburg Onno, Foijer Floris, Snippert Hugo J G, Kops Geert J P L mei 2019, In: Nature Genetics. 51 , p. 824-834 11 p.

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells

Huels D. J., Bruens L., Hodder M. C., Cammareri P., Campbell A. D., Ridgway R. A., Gay D. M., Solar-Abboud M., Faller W. J., Nixon C., Zeiger L. B., McLaughlin M. E., Morrissey E., Winton D. J., Snippert H. J., Van Rheenen J., Sansom O. J. 1 dec 2018, In: Nature Communications. 9

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

Oost Koen C., van Voorthuijsen Lisa, Fumagalli Arianna, Lindeboom Rik G.H., Sprangers Joep, Omerzu Manja, Rodriguez-Colman Maria J., Heinz Maria C., Verlaan-Klink Ingrid, Maurice Madelon M., Burgering Boudewijn M.T., van Rheenen Jacco, Vermeulen Michiel, Snippert Hugo J.G. 6 feb 2018, In: Cell Reports [E]. 22 , p. 1600-1614 15 p.

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

Fumagalli Arianna, Suijkerbuijk Saskia J.E., Begthel Harry, Beerling Evelyne, Oost Koen C., Snippert Hugo J., Van Rheenen Jacco, Drost Jarno 1 feb 2018, In: Nature Protocols. 13 , p. 235-247 13 p.

Live imaging of cell division in 3D stem-cell organoid cultures

Bolhaqueiro Ana C.F., van Jaarsveld Richard H., Ponsioen Bas, Overmeer René M., Snippert Hugo J., Kops Geert J.P.L. 1 jan 2018, 145 , p. 91-106 16 p.

Expanding the Tissue Toolbox:Deriving Colon Tissue from Human Pluripotent Stem Cells

Bruens Lotte, Snippert Hugo J.G. 6 jul 2017, In: Cell Stem Cell. 21 , p. 3-5 3 p.

Interplay between metabolic identities in the intestinal crypt supports stem cell function

Rodríguez-Colman Maria J, Schewe Matthias, Meerlo Maaike, Stigter Edwin, Gerrits Johan, Pras-Raves Mia, Sacchetti Andrea, Hornsveld Marten, Oost Koen C, Snippert Hugo J, Verhoeven-Duif Nanda, Fodde Riccardo, Burgering Boudewijn M T 2017, In: Nature. 543 , p. 424-427 4 p.

All Research Output (33)