prof. dr. C.K. (Cornelis) van der Ent Full Professor
- Speerpunt Child Health
- Pulmonology patient care
The research interests of professor Kors van der Ent focus on the themes Cystic Fibrosis and other bronchusobstructive diseseases in young children. He is the leader of the national HIT-CF program which focuses on the development and personalised application of new drugs influencing the basis genetic defect in patients with CF. This program includes both mechanistic studies in collaboration with the Hubrecht lab and the Byvoet Center as well as studies into host pathogen interaction in collaboration with the veterinary faculty of the Utrecht University. Clinical studies are performed in close collaboration with other CF-centres throughout Europe. Furthermore, he was the founder of the Whistler birth cohort, in which thousands of children are followed from birth to study determinants of the development of respiratory diseases. These cohorts mirror normal development to understand mechanisms in disease.
Kors van der Ent has special interest in innovation and valorisation in medical care and believes in creation of hospital networks to build the future medical care system for children. He successfully developed new devices to measure neonatal lung function, which were launched to the market. He also developed the Luchtwegportaal, an interactive web-based system to collect patient data regarding respiratory diseases in many hospitals in The Netherlands.
Chairman of Cystic Fibrosis Center Utrecht
Chairman of Dutch Cystic Fibrosis Research Network
Member of Medical Advisory Board Dutch Cystic Fibrosis Committee
Member of Research committee Wilhelmina Children’s Hospital Utrecht
Member of Medical Ethical Committee University Medical Center Utrecht
Medical advisor of Sioux CCM
Board Member of Malawi Mission Work Team
Reviewer for Am J Resp Crit Care Med, European Respir J and many others
Fellowship and Awards
European CF young investigator meeting award 2011. A functional CFTR assay using primary cystic fibrosis organoids
European CF basic science meeting award 2011. Treatment with VX809 and VX770 in rectal CF organoids expressing uncommon CFTR genotypes
European CF basic science meeting award 2012. Characterizing altered inflammatory signaling in CFTR-defective
bronchial epithelial cells
National symposium Dutch CF foundation award 2011. Complement mediated phagocytosis is reduced in CF monocytes.