Haemophilia Activities List (HAL and PedHAL)

The Hemophilia Activities List (HAL) and Pediatric Hemophilia Activities List (PedHAL) are self-reported questionnaires about limitations in activities and participation for patients with haemophilia.

HAL (18 years and older)

The HAL contains 42 items across 7 domains: lying down/sitting/kneeling/standing, functions of the legs, functions of the arms, use of transportation, self-care, household tasks and leisure activities and sports. Items are scored on a 6-point Likert scale (‘impossible’, ‘always’, ‘usually’, ‘sometimes’, ‘almost never’, ‘never’), with a ‘not applicable’ option for some items.  A summary score as well as component scores (upper extremity, basic lower extremity and complex lower extremity) can be calculated. The scores are converted to a normalized score from 0 to 100, where higher scores represent a better functional status. Click here for the HAL questionnaire.

PedHAL (4 to 18 years)

The PedHAL contains 53 items across 7 domains: sitting/kneeling/standing, functions of the legs, functions of the arms, use of transportation, self-care, household tasks and leisure activities and sports. It consists of a patient version (8-18 years) and parent version (4-18 years). Items are scored on a 6-point Likert scale (‘impossible’, ‘always’, ‘usually’, ‘sometimes’, ‘almost never’, ‘never’), with a ‘not applicable (N/A)’ scoring option for all items. A summary score as well as domain scores can be calculated. The scores are converted to a normalized score from 0 to 100, where higher scores represent a better functional status. Click here for the PedHAL questionnaire.

Available languages

Both the HAL and PedHAL are available in the following languages:

• Arabic (Emirates)
• Arabic (Egypt, Israel)
• Bengali
• Bulgarian
• Catalan
• Czech
• Chinese (simplified)
• Chinese (traditional)
• Croatian
• Danish
• Dutch
• English – for Australia
• English – for UK
• English – for USA and Canada
• Estonian
• Finnish
• Flemish
• French – for France
• French – for Canada
• Georgian
• German
• Greek
• Gujarati
• Hebrew
• Hindi
• Hungarian
• Indonesian (Bahasa)
• Irish
• Italian
• Japanese
• Kannada
• Korean
• Kurmanji
• Lettish
• Lituanian
• Malay
• Malayalam
• Marathi
• Norwegian
• Oriya (Odia)
• Polish
• Portugese – for Brazil
• Portugese – for Portugal
• Punjabi
• Romanian
• Russian
• Serbian
• Sesotho
• Slovak
• South African
• Spanish 
• Spanish - for latin America
• Swedish
• Tamil
• Telegu
• Thai
• Turkey
• Ukrainian
• Xhosa
• Zulu

Costs

The HAL and PedHAL translations are available free of charge for clinical use and research by non-commercial parties. For projects initiated or funded by (pharmaceutical) companies or when data will be shared with (pharmaceutical) companies, the costs for the translations are €3500 per language for either the HAL or the PedHAL (children and parent version) and €6000 per language for both the HAL and PedHAL (children and parent version).

Request form for (Ped)HAL translations

Please complete the HAL Request Form if you are interested in receiving or purchasing the HAL and PedHAL translations.

References

1. Timmer, M. A., Gouw, S. C., Feldman, B. M., Zwagemaker, A., de Kleijn, P., Pisters, M. F., Schutgens, R. E. G., Blanchette, V., Srivastava, A., David, J. A., Fischer, K., & van der Net, J. (2017). Measuring activities and participation in persons with haemophilia: A systematic review of commonly used instruments. Haemophilia : The Official Journal of the World Federation of Hemophilia. 

HAL

1. Batt, K., Recht, M., Cooper, D. L., & Iyer, N. N. (2017). Construct validity of patient-reported outcome instruments in us adult people with hemophilia (PWH): Results from the pain, functional impairment, and quality of life (P-FIQ) study. Value in Health, 19(3), A93. 
2. Brodin, E., Baghaei, F., Elfvinger, P., Lindvall, K., & Sunnerhagen, K. S. (2011). The Swedish version of the Haemophilia Activity List. Haemophilia, 17(4), 662–668. 
3. Van Genderen FR, van Meeteren NLU, van der Bom JG, et al. Functional consequences of haemophilia in adults: The development of the Haemophilia Activities List. Haemophilia 2004; 10: 565–71.
4. Van Genderen FR, Westers P, Heijnen L, et al. Measuring patients’ perceptions on their functional abilities: Validation of the Haemophilia Activities List. Haemophilia 2006; 12: 36–46.
5. McLaughlin P, Morris R, Chowdary P. Investigating the relationship between the HJHS and HAL in routine clinical practice: A retrospective review. Haemophilia 2018; 24:988-994.
6. Kuijlaars, I. A. R., van Emst, M., van der Net, J., Timmer, M. A., & Fischer, K. (2020). Assessing the test–retest reliability and smallest detectable change of the Haemophilia Activities List. Haemophilia, November, 1–5.

PedHAL

1. Groen WG, van der net J, Helders PJM, Fischer K. Development and preliminary testing of a Paediatric Version of the Haemophilia Activities List (Pedhal). Haemophilia 2010; 16: 281–9.
2. Groen W, Van der Net J, Lacatusu AM, et al. Functional limitations in Romanian children with haemophilia: Further testing of psychometric properties of the Paediatric Haemophilia Activities List. Haemophilia 2013; 19: 116–25.
3. Kuijlaars IAR, van der Net J, Schutgens REG, Fischer K. The Paediatric Haemophilia Activities List (PedHAL) in routine assessment: changes over time, child-parent agreement and informative domains. Haemophilia 2019; 25: 953–9.
4. Radzevič V, Raistenskis J, Ragelienė L, Kowalski IM. Relationship between physical activity and functional ability in school-aged children with hemophilia. Polish Ann Med 2013; 20: 13–8.