prof. dr. A.C.G. (Toine) Egberts

Full Professor

  • Clinical Pharmacy

prof. dr. A.C.G. (Toine) Egberts


Toine Egberts (1965) obtained his PharmD in 1990 at the University of Groningen, the Netherlands. Thereafter he was trained as a clinical pharmacist during four years in the hospitals of Tilburg and Delft. In 1994, he started his PhD project at the department of Pharmacoepidemiology & Clinical Pharmacology of Utrecht University in collaboration with the Netherlands Pharmacovigilance Foundation 'Lareb'. This resulted in 1997 in a thesis entitled 'Pharmacoepidemiologic approaches to the evaluation of antidepressant drugs'. During his PhD-project he obtained the Master of Science degree in clinical epidemiology at the Netherlands Institute of Health Sciences.

He was appointed in 2001 as professor of clinical pharmacoepidemiology at the department of Pharmacoepidemiology & Clinical Pharmacology. Since 2006 he is also a professor of clinical pharmacy at the medical faculty of Utrecht University. In these positions he tries to bridge the drug environment and the patient environment.

From 2006 - 2017 he was the chief pharmacist of the department of clinical pharmacy of the University Medical Center Utrecht.

Since november 2018 he is director of doctor education of the Graduate School of Life Sciences of the Utrecht University. The coaching of PhD students gives him energy as it nicely balances performing research into medical/pharmaceutical puzzles with the personal development of young academic professionals. He had the opportunity to guide over 60 PhD students towards the 'hora est'. He has always been deeply involved in education, especially the training of hospital pharmacists, for which he received in 2016 the 'Senior Jan Glerum Award'.

He is (co)author of over 450 international peer reviewed scientific publications and a reviewer for several scientific journals and international research funding organisations.

He is a member of the editorial board of the journal Drug Safety. He is member of several committees such as the CCMO, the Netherlands Expertcenter for Pharmacotherapy for older people (EPHOR), the scientific advisory board of the Mental Health Center of the University of Wurzburg.

His research activities focus on a) the clinical pharmacology / clinical pharmacoepidemiology of drugs used in the treatment of psychiatric and neurologic disorders, and b) on innovations in clinical pharmacy systems.

He is married to Karin, has two daughters (Bibi and Louisa) and one son (Kilian) and in his spare time he likes to (trail)run, bootcamp, climb mountains and to play / listen to music.

Side Activities

  • All mentioned activities are current:

    • professor of clinical pharmacy, department of pharmaceutical sciences Utrecht University
    • director of doctoral education Graduate School of Life Sciences Utrecht University
    • member CCMO
    • advisor clinical pharmacology group Jeroen Bossch Ziekenhuizen
    • member of the working group for a clinical guideline on deprescribing Quality Insitute Federation Medical Specialists
    • reviewer of project proposals for funding organizsations such as ZonMw
    • member of the editorial board of the journal Drug Safety
    • reviewer for several biomedical journals
    • board member of the Netherlands Expertcenter for Pharmacotherapy for older people (EPHOR)
    • chiar of the stichting KNMP fondsen
    • member scientific advisory board Zentrum fur Psychische Gesundheit, Uniklinikum Wurzburg, Germany

Fellowship and Awards

  • Huizinga Penning (2004)

    Senior Jan Glerum prijs (2016)

Research Output (488)

Discontinuation Rates of Antidepressant Use by Dutch Soldiers

Janssen Debbie G.A., Vermetten Eric, Egberts Toine C.G., Heerdink Eibert R. 1 dec 2019, In: Military Medicine. 184 , p. 868-874 7 p.

Associations between personality traits and adequate home storage of drugs in older patients

Vlieland N. D., van den Bemt B. J.F., Wouters H., Egberts A. C.G., Bouvy Marcel, Gardarsdottir H. 26 nov 2019, In: Psychology, Health and Medicine. 24 , p. 1255-1266 12 p.

The effect of a pharmaceutical transitional care program on rehospitalisations in internal medicine patients:An interrupted-time-series study

Karapinar-Çarklt Fatma, Borgsteede Sander D., Janssen Marjo J.A., Mak Marlies, Yildirim Nimet, Siegert Carl E.H., Mol Peter G.M., Egberts Toine C.G., Van Den Bemt Patricia M.L.A. 21 okt 2019, In: BMC Health Services Research. 19

Effect of reimbursement restriction policy on the use of benzodiazepines in the Netherlands:An interrupted time series analysis

Stoker Lennart Jan, Heerdink Eibert Roelof, Janssen Richard, Egberts Toine C.G. 1 sep 2019, In: BMJ Open. 9

Pharmacist-Psychiatrist Interventions Triggered by Clinical Decision Support System Improve Monitoring of Patients Using Lithium in a General Hospital

Van Gorp Freek, Kuck Emile M., Sonnen Max P.A.M., Hugenholtz Gerard W.K., Egberts Toine C.G., Wilting Ingeborg 1 sep 2019, In: Journal of Clinical Psychopharmacology. 39 , p. 532-533 2 p.

Unbound Fraction of Clozapine Significantly Decreases with Elevated Plasma Concentrations of the Inflammatory Acute-Phase Protein Alpha-1-Acid Glycoprotein

Man Wai Hong, Wilting Ingeborg, Heerdink Eibert R., Hugenholtz Gerard W.K., Bognár Tim, ten Berg Maarten J., van Solinge Wouter W., Egberts Toine A.C.G., van Maarseveen Erik M. 1 aug 2019, In: Clinical Pharmacokinetics. 58 , p. 1069-1075 7 p.

Exploring the Association between Monoclonal Antibodies and Depression and Suicidal Ideation and Behavior:A VigiBase Study

Minnema Lotte A, Giezen Thijs J, Souverein Patrick C, Egberts Toine C G, Leufkens Hubert G M, Gardarsdottir Helga jul 2019, In: Drug Safety. 42 , p. 887-895 9 p.

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia

Favié Laurent M.A., Groenendaal Floris, Van Den Broek Marcel P.H., Rademaker Carin M.A., De Haan Timo R., Van Straaten Henrica L.M., Dijk Peter H., Van Heijst Arno, Simons Sinno H.P., Dijkman Koen P., Rijken Monique, Zonnenberg Inge A., Cools Filip, Zecic Alexandra, Van Der Lee Johanna H., Nuytemans Debbie H.G.M., Van Bel Frank, Egberts Toine C.G., Huitema Alwin D.R. 28 jun 2019, In: Neonatology. 116 , p. 154-162 9 p.

Willingness of patients to use unused medication returned to the pharmacy by another patient: a cross-sectional survey

Bekker Charlotte, van den Bemt Bart, Egberts Toine CG, Bouvy Marcel, Gardarsdottir Helga 14 mei 2019, In: BMJ Open. 9

Redispensing of unused HIV post-exposure prophylaxis for medical students

Bekker Charlotte L, Kalicharan Raween W, Melis Eward J, Gardarsdottir Helga, van den Bemt Bart J F, Bouvy Marcel L, van Maarseveen Erik M, Egberts Antoine C G 1 mei 2019, In: Travel Medicine and Infectious Disease. 29 , p. 82-83 2 p.

All Research Output (488)