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prof. dr. F.W. (Folkert) Asselbergs Full Professor

  • Department of Cardiology

F.W. Asselbergs

Contact

Research Programs

Biography

Prof Folkert W. Asselbergs is Prof in cardiovascular genetics and consultant cardiologist at the department of Cardiology, University Medical Center Utrecht, Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Health Informatics, University College London, Director BRC Clinical Research Informatics Unit, University College London Hospital, Manager Research Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliane.nl).

 

Professor Asselbergs published more than 300 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org) are the most prominent ones. He is scientific coordinator of European IMI Bigdata@Heart consortium (www.bigdata-heart.eu). BigData@Heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insights driving drug development and personalized medicine through advanced big-data analytics. 

 

 

 

 

Side Activities

    • Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Director
    • Director Clinical Research Informatics Unit, University College London HospitalHealth Informatics, University College London
    • Medical Scientific Board Member "Deep".
    • Manager Research Center for Circulatory Health, UMC Utrecht

Fellowship and Awards

  • 2014 - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation (2014T001)

    2012 - Fellow of the European Society of Cardiology

    2010 - Clinical fellowship from the Netherlands Organisation for Health Research and Development(ZonMw grant 90700342)

    2003  - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation(NHS 2003T010)

Research Output (282)

Age at menarche and heart failure risk:The EPIC-NL study

Plompen Mitchell V L, van der Schouw Yvonne T, Rutten Frans H, Verschuren W M Monique, Boer Jolanda M A, Asselbergs Folkert W, Onland-Moret N Charlotte jan 2020, In: Maturitas. 131 , p. 34-39 6 p.

Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis:The SMART-MR Study

Zwartbol M. H. T., Geerlings M. I., Ghaznawi R., Hendrikse J., van der Kolk A. G., Asselbergs F. W., Nathoe H. M., de Borst G. J., Bots M. L., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren F. L. J., Westerink J., 5 dec 2019, In: American Journal of Neuroradiology. 40 , p. 2016-2022 7 p.

Sequence variants with large effects on cardiac electrophysiology and disease

Norland Kristjan, Sveinbjornsson Gardar, Thorolfsdottir Rosa B., Davidsson Olafur B., Tragante Vinicius, Rajamani Sridharan, Helgadottir Anna, Gretarsdottir Solveig, van Setten Jessica, Asselbergs Folkert W., Sverrisson Jon Th, Stephensen Sigurdur S., Oskarsson Gylfi, Sigurdsson Emil L., Andersen Karl, Danielsen Ragnar, Thorgeirsson Gudmundur, Thorsteinsdottir Unnur, Arnar David O., Sulem Patrick, Holm Hilma, Gudbjartsson Daniel F., Stefansson Kari 1 dec 2019, In: Nature Communications. 10 10 p.

Cancer Therapy-Related Cardiac Dysfunction of Nonanthracycline Chemotherapeutics. What Is the Evidence?

Kamphuis Janine, Linschoten Marijke, Cramer Maarten J, Gort Eelke, van Rhenen Anna, Asselbergs Folkert, Doevendans PA, Teske Arco 1 dec 2019, In: JACC. Cardio Oncology. 1 , p. 280-290 10 p.

Associations of autozygosity with a broad range of human phenotypes

Clark David W et al. 1 dec 2019, In: Nature Communications. 10

Association of troponin level and age with mortality in 250 000 patients:cohort study across five UK acute care centres

Kaura Amit, Panoulas Vasileios, Glampson Benjamin, Davies Jim, Mulla Abdulrahim, Woods Kerrie, Omigie Joe, Shah Anoop D, Channon Keith M, Weber Jonathan N, Thursz Mark R, Elliott Paul, Hemingway Harry, Williams Bryan, Asselbergs Folkert, O'Sullivan Michael, Kharbanda Rajesh, Lord Graham M, Melikian Narbeh, Patel Riyaz S, Perera Divaka, Shah Ajay M, Francis Darrel P, Mayet Jamil 20 nov 2019, In: BMJ (Clinical research ed.). 367 , p. l6055

A genotype-guided strategy for oral P2Y<sub>12</sub> inhibitors in primary PCI

Claassens Daniel M.F., Vos Gerrit J.A., Bergmeijer Thomas O., Hermanides Renicus S., Van’t Hof Arnoud W.J., Van Der Harst Pim, Barbato Emanuele, Morisco Carmine, Tjon Joe Gin Richard M., Asselbergs Folkert W., Mosterd Arend, Herrman Jean Paul R., Dewilde Willem J.M., Janssen Paul W.A., Kelder Johannes C., Postma Maarten J., De Boer Anthonius, Boersma Cornelis, Deneer Vera H.M., ten Berg Jurriën M. 24 okt 2019, In: New England Journal of Medicine. 381 , p. 1621-1631 11 p.

A genotype-guided strategy for oral P2Y<sub>12</sub> inhibitors in primary PCI

Claassens Daniel M.F., Vos Gerrit J.A., Bergmeijer Thomas O., Hermanides Renicus S., Van’t Hof Arnoud W.J., Van Der Harst Pim, Barbato Emanuele, Morisco Carmine, Tjon Joe Gin Richard M., Asselbergs Folkert W., Mosterd Arend, Herrman Jean Paul R., Dewilde Willem J.M., Janssen Paul W.A., Kelder Johannes C., Postma Maarten J., De Boer Anthonius, Boersma Cornelis, Deneer Vera H.M., ten Berg Jurriën M. 24 okt 2019, In: New England Journal of Medicine. 381 , p. 1621-1631 11 p.

The Netherlands Arrhythmogenic Cardiomyopathy Registry:design and status update

Bosman L. P., Verstraelen T. E., van Lint F. H.M., Cox M. G.P.J., Groeneweg J. A., Mast T. P., van der Zwaag P. A., Volders P. G.A., Evertz R., Wong L., de Groot N. M.S., Zeppenfeld K., van der Heijden J. F., van den Berg M. P., Wilde A. A.M., Asselbergs F. W., Hauer R. N.W., te Riele A. S.J.M., van Tintelen J. P., Baas A. F., Barge-Schaapveld D. Q.C.M., Boekholdt S. M., Cramer M. J.M., Dooijes D., Jongbloed J. D.H., Loh P., Planken R. N., Prakken N. H.J., van der Smagt J. J., van der Wal A. C., Teske A. J., van Veen T. A.B., Velthuis B. K., Vink A., Yap S. C., 1 okt 2019, In: Netherlands Heart Journal. 27 , p. 480-486 7 p.

Association between beta-blocker use and mortality/morbidity in older patients with heart failure with reduced ejection fraction A propensity score-matched analysis from the Swedish Heart Failure Registry

Stolfo Davide, Uijl Alicia, Benson Lina, Schrage Benedikt, Fudim Marat, Asselbergs Folkert W, Koudstaal Stefan, Sinagra Gianfranco, Dahlström Ulf, Rosano Giuseppe, Savarese Gianluigi 3 sep 2019, In: European Journal of Heart Failure. 22 , p. 103-112 10 p.

All Research Output (282)
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