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prof. dr. E.J.H.J. (Emmanuel) Wiertz

Full Professor

  • Department of Medical Microbiology

Research Output (71)

Splenic Red Pulp Macrophages Cross-Prime Early Effector CTL That Provide Rapid Defense against Viral Infections

Enders Marika, Franken Lars, Philipp Marie-Sophie, Kessler Nina, Baumgart Ann-Kathrin, Eichler Melanie, Wiertz Emmanuel J H, Garbi Natalio, Kurts Christian 1 jan 2020, In: Journal of Immunology. 204 , p. 87-100 14 p.

Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter

Wąchalska Magda, Graul Małgorzata, Praest Patrique, Luteijn Rutger D, Babnis Aleksandra W, Wiertz Emmanuel J H J, Bieńkowska-Szewczyk Krystyna, Lipińska Andrea D 7 dec 2019, In: Cells. 8

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection

Luteijn Rutger D, van Diemen Ferdy, Blomen Vincent A, Boer Ingrid G J, Manikam Sadasivam Saravanan, van Kuppevelt Toin H, Drexler Ingo, Brummelkamp Thijn R, Lebbink Robert Jan, Wiertz Emmanuel J 1 jul 2019, In: Journal of Virology. 93

A flow cytometry-based approach to unravel viral interference with the MHC class I antigen processing and presentation pathway

Praest Patrique, de Buhr Hendrik, Wiertz Emmanuel J.H.J. 31 mei 2019, p. 187-198 12 p.

Transmembrane regions of bovine herpesvirus 1-encoded UL49.5 and glycoprotein M regulate complex maturation and ER-Golgi trafficking

Graul Malgorzata, Kisielnicka Edyta, Rychlowski Michal, Verweij Marieke C., Tobler Kurt, Ackermann Mathias, Wiertz Emmanuel J.H.J., Bieńkowska-Szewczyk Krystyna, Lipińska Andrea D. 1 mrt 2019, In: Journal of General Virology. 100 , p. 497-510 14 p.

The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins

Praest P., Luteijn R. D., Brak-Boer I. G.J., Lanfermeijer J., Hoelen H., Ijgosse L., Costa A. I., Gorham R. D., Lebbink R. J., Wiertz E. J.H.J. 4 jun 2018, In: Molecular Immunology. 101 , p. 55-64 10 p.

Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol

Luteijn Rutger David, Drexler Ingo, Smith Geoffrey L, Lebbink Robert Jan, Wiertz Emmanuel J H J jun 2018, In: Journal of General Virology. 99 , p. 790-804 15 p.

Endocytosed soluble cowpox virus protein CPXV012 inhibits antigen cross-presentation in human monocyte-derived dendritic cells

Spel Lotte, Luteijn Rutger D., Drijfhout Jan W., Nierkens Stefan, Boes Marianne, Wiertz Emmanuel J.H. 8 feb 2018, In: Immunology and Cell Biology. 96 , p. 137-148

New insights into the structure of the MHC class I peptide-loading complex and mechanisms of TAP inhibition by viral immune evasion proteins

Praest Patrique, Liaci A Manuel, Förster Friedrich, Wiertz Emmanuel J H J 2018, In: Molecular Immunology. 113 , p. 103-114 12 p.

Multiple E2 ubiquitin-conjugating enzymes regulate human cytomegalovirus US2-mediated immunoreceptor downregulation

van de Weijer Michael L., Schuren Anouk B.C., Boomen Dick J.H., Mulder Arend, Claas Frans H J, Lehner Paul J., Lebbink Robert Jan, Wiertz Emmanuel J.H.J. 1 sep 2017, In: Journal of Cell Science. 130 , p. 2883-2892 10 p.