Intracranial aneurysms & subarachnoid hemorrhage
Intracranial aneurysms & subarachnoid hemorrhage is ….
The research group on unruptured intracranial aneurysms and subarachnoid hemorrhage at the UMC Utrecht is one of the largest groups in this field worldwide. We aim to elucidate mechanisms of aneurysm formation and rupture, to develop screening strategies for high-risk individuals, and to improve prognosis after aneurysm rupture. Various experts, specialized in genetics, microglia biology, neuroimaging, neurology, neurosurgery, neuropsychology, and rehabilitation medicine closely work together. Novel treatment strategies are being tested in preclinical studies and multicenter clinical trials. We have a strong international network.
Principal investigators
Tristan van Doormaal
Elly Hol
Gabriel Rinkel
Ynte Ruigrok
Irene van der Schaaf
Birgitta Velthuis
Mervyn Vergouwen
Anne Visser-Meily
Martine van Zandvoort
Bart van der Zwan
Clinical trials
- PROTECT-U (Prospective Randomized Open-label Trial to Evaluate risk faCTor management in patients with Unruptured intracranial aneurysms). www.protect-u-trial.com
- CLASH (CompLement C5 Antibodies for decreasing brain injury after aneurysmal Subarachnoid Hemorrhage)