Marcel van der Heyden
I am an associate professor in the department of Medical Physiology at the University Medical Center Utrecht, The Netherlands. After my training in cell, developmental and stem cell biology, I entered the field of cardiac arrhythmias in the year 2000. Currently, my focus is on potassium ion channel biology and pharmacology. My group works on the mechanisms on pharmacological activation and inhibition of cardiac potassium channels to prevent or suppress cardiac arrhythmia. Furthermore, we aim to unravel the intricate mechanisms of cardiac ion channel trafficking, its disturbances associated with cardiac disease and pharmacological rescue of mis-trafficking, which results made the cover of Molecular Pharmacology. We also determine functional defects of patient-derived channel mutations, for example on our hospitals seminal work on Cantú syndrome.
I’m associate editor on four peer review physiology and pharmacology journals, including Frontiers in Physiology and the British Journal of Pharmacology.
Finally, I have an interest in research integrity and teach on responsible conduct of research within our Graduate School of Life Sciences and many other national and international universities, and publish on scientific misconduct.
Contact
Email address: m.a.g.vanderheyden@umcutrecht.nl
Phone: 088 7558901
Keywords research
Cardiac physiology, Potassium ion channels, Cardiac arrhythmia, Ion channel trafficking, Scientific integrity
Research topic
Cardiac ion channel biology and pharmacology
Type of research
Molecular and cellular biology, biochemistry, patch clamp electrophysiology, large animal cardiac electrophysiology
Collaborations / partnerships
- Dr. Anna Stary-Weinzinger. University of Vienna
- Dr. Brian Delisle. University of Kentucky
- Prof. Dr. Ricardo Caballero. Complutense University of Madrid
- Prof. Dr. Niels Voigt. University Medical Center Goettingen
- Prof. Dr. Ad IJzerman. Leiden University
- Dr. Sander Verheule. Maastricht University.
- Dr. Peter van Hasselt