Group Booes, Optimizing immune recognition
My lab explores mechanisms that drive immune recognition in human disease. It is becoming increasingly clear that many diseases have an inflammatory component to them that may be treatable by immune response modification. Cancer is one such disease, that touches on many aspects of immune recognition. Our approach to finding mechanisms in human disease is to study common traits in diseases of limited complexity (primary immunodeficiencies presenting with autoinflammation) and conditions of increasing complexity (rheumatoid disorders, cancer). From 2003-2008, my laboratory was located at Harvard Medical School/Brigham and Women’s Hospital in Boston, USA. Since 2008, we are located at UMC-Utrecht.
Research interests / topics uitklapper, klik om te openen
- Immunology
- Antigen presentation
- Immune recognition
- Human disease
- Pediatric
About the group leader(s) uitklapper, klik om te openen
Marianne Boes is chair of the Young Academy of the UMC Utrecht and board member of the Center for Unusual Collaborations (CUCo; working group of the Young Academies of the Strategic Alliance between TU-Eindhoven, Wageningen, Utrecht University and UMC-Utrecht). Boes is Faculty of Medicine-biomedical sciences member of the Education Committee of the Graduate School of Life Sciences (EC-LS), and serves as coordinator of the course 'Advanced Immunology' for PhD students, and the MSc course Logical Argumentation in Science: Publishing, Proposals and Pitching (co-coordinating with Dr. Eric Kalkhoven). Outside activities include her role as editor for several immunology and immunotherapy journals, membership of ZonMw evaluation committees and of data safety monitoring boards for clinical studies. She thoroughly enjoys to meet and learn from researchers, patients and societal partners in different fields. She works actively to improve the involvement of patients and their perspectives in translational research.
Related websites
Group members
Associated clinical researchers
- Henk Schipper
- Lilly Verhagen
- Joris van Montfrans
- Roger Schutgers
- Friederike Meyer-Wentrup
PhD Students
- Sarah Schep
- Francesca Ververs
- Bas Smits
- Mischa Koenen
- Juliette Pouw
- Nila Servaas
- Patrick Greve
- Angela Markovska
- Niels van Heusden
Education / Courses uitklapper, klik om te openen
Educational Comittee Life Sciences
Since 2017, Marianne Boes is a staff member of the Educational Comittee Life Sciences that assesses and ensures the quality of education of the master's programmes within the Graduate School of Life Sciences.
Achievements
Funding & Grants
Awards/Achievements/Prizes
Collaborations uitklapper, klik om te openen
van Creveldkliniek
Prof Dr Roger Schutgens, Dr. Kathelijn Fischer
Princes Maxima Centrum voor Kinderoncologie
Dr. Friederike Meyer-Wentrup
UU Veterinary Department
Prof. Dr. Willem Stoorvogel
Molecular Cancer Research
Dr. Eric Kalkhoven
Boston Children's Hospital
Prof. Dr. Hidde Ploegh